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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CBLB rabbit polyclonal antibody |
Gene Name: | E3 ubiquitin-protein ligase CBL-B |
Synonyms: | Cblb, CBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B |
Immunogen: | Recombinant protein corresponding to Mouse CBLB |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 109 kDa |
Observed MW. | 109 kDa |
Uniprot ID: | Q13191 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HepG2, MCF7, U87 |
Background
CBL-B functions as a negative regulator of T-cell activation. CBL-B expression in T cells causes ligand-induced T cell receptor down-modulation, controlling the activation degree of T cells during antigen presentation.
Images
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Western blot analysis of cblb (GB11732) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
