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Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CCL3 rabbit polyclonal antibody |
Gene Name: | C-C motif chemokine 3 |
Synonyms: | Heparin-binding chemotaxis protein, L2G25B, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, SIS-alpha, Small-inducible cytokine A3, TY-5, Ccl3, Mip1a, Scya3 |
Immunogen: | Recombinant protein corresponding to Mouse CCL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P10855, P50229 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | pneumonia, spleen, splenitis |
Background
The MIP-1 alpha is a monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.MIP-1 proteins have been reported to have multiple effects on hematopoietic precursor cells and MIP-1 alpha has been identified as a stem cell inhibitory factor that can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. The functional receptor for MIP-1 alpha has been identified as CCR1 and CCR5.
Images
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Immunohistochemistry of paraffin embedded mouse pneumonia using CCL3 (GB111212) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse spleen using CCL3 (GB111212) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse splenitis using CCL3 (GB111212) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat pneumonia using CCL3 (GB111212) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat splenitis using CCL3 (GB111212) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
