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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TCPB rabbit polyclonal antibody |
Gene Name: | T-complex protein 1 subunit beta |
Synonyms: | TCP-1-beta, CCT-beta, CCT2, CCTB, 99D8.1, Chaperonin containing t complex polypeptide 1 subunit 2, Chaperonin containing TCP1 subunit 2, MGC142074, MGC142076, MGC94480, Phosphocholine cytidylyltransferase 2, CTP, PRO1633, TCPB |
Immunogen: | Recombinant protein corresponding to Mouse CCT2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 57 kDa |
Uniprot ID: | P78371, P80314, Q5XIM9 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500- 1: 1000 | lung, kidney, brain |
Background
TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). consists of 2 back to back rings, each containing eight different proteins. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin and tubulin, as well as alpha transducin. TCP1 delta belongs to the TCP1 chaperonin family, assisting the folding of proteins upon ATP hydrolysis. Alternate transcriptional splice variants of the TCP-1 beta gene have A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.
Images
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Western blot analysis of TCPB (GB11981) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
