Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CD103 rabbit polyclonal antibody |
Gene Name: | Integrin alpha-E |
Synonyms: | Integrin alpha M290, CD103, Integrin alpha-E light chain, Itgae |
Immunogen: | Recombinant protein corresponding to Mouse CD103 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 129 kDa |
Observed MW. | 150 kDa |
Uniprot ID: | P38570, Q60677, M0R6T8 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | thymus, testis |
Background
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
Images
Western blot analysis of CD103 (GB111142) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |