Reactivity: | H,M,R & H,M,R & H,M,R |
Applications: | WB & IHC/IF & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | CD109 antigen |
Synonyms: | CD109, CD109 antigen, CD109 molecule, CPAMD7, p180, Platelet specific Gov antigen, r150, RP11 525G3.1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CD109 |
Uniprot ID: | Q8R422 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 162 kDa / 190 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung |
Background
CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor.
Images
Western blot analysis of CD109 (GB115310) at dilution of 1:1000 | |
Western blot analysis of CD109 (GB115310) at dilution of 1:1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |