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Anti-CD169 (Sialoadhesin) Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: |
CD169 rabbit polyclonal |
| Gene Name: |
Sialoadhesin |
|
Synonyms: |
Sialic Acid Binding Ig Like Lectin 1, Sialoadhesin, SIGLEC-1, SN, CD1 |
| Immunogen: |
KLH conjugated Synthetic peptide corresponding to Mouse CD169 |
| Isotype: | IgG |
| Purity: | Affinity purification |
| Subcellular location: |
Cell membrane,Secreted |
| Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1:500-1:3000 | tonsil,lymph node |
IF | Human, Mouse, Rat | 1:500-1:1000 | tonsil,lymph node |
Background
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.
Images
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Immunohistochemistry analysis of paraffin-embedded human tonsil using CD169(GB11299) at dilution of 1:500 |
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Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD169(GB11299) at dilution of 1:500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
