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| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | B-lymphocyte antigen CD19 |
Synonyms: | CD19, B4, CVID3, CD19 molecule |
Immunogen: | Human recombinant CD19 protein expressed in HEK293 cells |
Uniprot ID: | P15391 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 60 kDa / 90-120 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | Raji |
IHC/IF | Human | 1: 500-1: 1500 | tonsil,lymphoma, lung squamous cell carcinoma |
Background
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Images
| Western blot analysis of CD19 (GB12061) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human tonsil using CD19 (GB12061) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human lymphoma using CD19 (GB12061) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human lung squamous cell carcinoma using CD19 (GB12061) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
