Reactivity: | H & H |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | T-cell surface antigen CD2 |
Synonyms: | CD2 molecule, Erythrocyte receptor, LFA 2, LFA 3 receptor, Rosette receptor, SRBC, T cell surface antigen CD2, T11 |
Immunogen: | Recombinant protein corresponding to Human CD2 |
Uniprot ID: | P06729 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 39 kDa / 48-65 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | Jurkat, Molt4 |
IHC/IF | Human | 1: 1200-1: 2400 | tonsil, stomach, lung adenocarcinoma |
Background
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Images
Western blot analysis of CD2 (GB115274) at dilution of 1:1000 | |
Immunohistochemistry analysis of paraffin embedded human tonsil using CD2 (GB115274) at dilution of 1: 2800 | |
Immunohistochemistry analysis of paraffin embedded human stomach using CD2 (GB115274) at dilution of 1: 2800 | |
Immunohistochemistry analysis of paraffin embedded human lung adenocarcinoma using CD2 (GB115274) at dilution of 1: 2800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |