Your shopping cart is empty!
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) |
Gene ID: | 960 |
Immunogen: | Synthesized peptide derived from human CD44 |
Uniprot ID: | P16070 |
Source: | Mouse/IgG2b, Kappa |
Concentration: | 1 mg/ml |
Purity: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
IHC/IF | Human | 1: 200-1: 500 | colon cancer, liver cancer, ovarian cancer |
Background
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. This protein exists in multiple forms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and extensive post-translational modifications.
Images
 |
Immunohistochemistry analysis of paraffin embedded human colon cancer using CD44 (GB14037) at dilution of 1: 100 |
 |
Immunohistochemistry analysis of paraffin embedded human liver cancer using CD44 (GB14037) at dilution of 1: 100 |
| Immunohistochemistry analysis of paraffin embedded human ovarian cancer using CD44 (GB14037) at dilution of 1: 100 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
