Reactivity: | H, M |
Applications: | FC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | CD44 antigen |
Synonyms: | CD44, CD44 antigen, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I |
Immunogen: | Recombinant protein corresponding to Mouse CD44 |
Uniprot ID: | P15379 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
FC | Human, Mouse | 1: 100-1: 200 | EL4+PMA 48h, Hela |
Background
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment.Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection.Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases.
Images
Flow cytometric analysis of CD44. Sample: EL4 (blue histogram), EL4 treated with PMA 48h (red histogram). Antibody: Alexa Fluor®488 conjugated Anti-CD44 Rabbit pAb (ZB115639-AF488), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. | |
Flow cytometric analysis of CD44. Sample: Hela. Antibody: Alexa Fluor®488 conjugated Anti-CD44 Rabbit pAb(ZB115639-AF488 red histogram), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. | |
Flow cytometric analysis of CD44. Sample: LNCap. Antibody: Alexa Fluor®488 conjugated Anti-CD44 Rabbit pAb(ZB115639-AF488 red histogram), 1: 100, RT 30 min. Control Antibody: FITC conjugated Goat Anti-Rabbit lgG (GB22303, open histogram), 1: 200, RT 30 min. |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |