Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CEBPZ rabbit polyclonal antibody |
Gene Name: | CCAAT/enhancer-binding protein zeta |
Synonyms: | Cebpz, CBF, CBF2, CCAAT binding factor, CEBPZ, HSP CBF, NOC1 |
Immunogen: | Recombinant protein corresponding to Mouse CEBPZ |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 120 kDa |
Observed MW. | 145 kDa |
Uniprot ID: | Q03701, P53569 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, ovary |
Background
The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML).
Images
Western blot analysis of CEBPZ (GB111498) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |