Reactivity: | R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CLEC2D rabbit polyclonal |
Gene Name: | C-type lectin domain family 2 member D |
Synonyms: | CLAX, CLEC2D, Lectin like NK cell receptor, Lectin like transcript 1, LLT1, LLT-1, Clec2d5, C type lectin related f, OCIL, Osteoclast inhibitory lectin |
Immunogen: | Recombinant protein corresponding to Mouse CLEC2D |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Rat | 1: 500-1: 1000 | spleen, thymus |
Background
CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts . Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs . CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and that their interaction differentially regulates NK- and T-cell functions . It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells.
Images
Western blot analysis of CLEC2D (GB113251) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |