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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Dual specificity protein kinase CLK3 |
Synonyms: | CDC like kinase 3; CDC-like kinase 3; CLK3; CLK3_HUMAN; Dual specificity protein kinase CLK3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CLK3 |
Uniprot ID: | O35492 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 74 kDa / 15/64 kDa |
Product Usage Information
WB | Mouse | 1: 300-1: 600 | ovary |
Background
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Images
| Western blot analysis of CLK3 (GB114619) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
