Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | COL6A1 rabbit polyclonal antibody |
Gene Name: | Collagen alpha-1(VI) chain |
Synonyms: | Col6a1, Alpha 1 (VI) chain (61 AA), Collagen VI, alpha 1 polypeptide, Collagen, intimal short chain collagen, Collagen, type VI, alpha 1 |
Immunogen: | Recombinant protein corresponding to Mouse COL6A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 108 kDa |
Observed MW. | 150 kDa |
Uniprot ID: | Q04857 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | cartilage, skin, graisse |
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Images
Western blot analysis of Collagen alpha-1(Ⅵ) (GB111380) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |