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Anti-CSRP3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CSRP3 rabbit polyclonal antibody |
Gene Name: | Cysteine and glycine-rich protein 3 |
Synonyms: | Cardiac LIM protein, CLP, CMD1M, CMH12, CRP3, CSRP3, Cysteine rich protein 3, LIM domain protein, cardiac, LMO4, MLP, Muscle LIM protein |
Immunogen: | Recombinant protein corresponding to Mouse CSRP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm, Cytoskeleton |
Uniprot ID: | P50462 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1000 | skeletal muscle, heart |
Background
Positive regulator of myogenesis. Acts as cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6. Enhances the DNA-binding activity of the MYOD1:TCF3 isoform E47 complex and may promote formation of a functional MYOD1:TCF3 isoform E47:MEF2A complex involved in myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation .
Images
| Immunohistochemistry of paraffin embedded mouse heart using CSRP3 (GB113951) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse skeletal muscle using CSRP3 (GB113951) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat skeletal muscle using CSRP3 (GB113951) at dilution of 1: 1000 (400x |
| Immunohistochemistry of paraffin embedded rat heart using CSRP3 (GB113951) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded embedded mouse heart using CSRP3 (GB113951) at dilution of 1: 1000 (400x lens) |
 | Immunofluorescence of paraffin embedded embedded rat heart using CSRP3 (GB113951) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
