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Anti-CX3CL1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CX3CL1 rabbit polyclonal antibody |
Gene Name: | Fractalkine |
Synonyms: | C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, Processed fractalkine, CX3CL1, FKN, NTT, SCYD1 |
Immunogen: | Recombinant protein corresponding to Human CX3CL1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Uniprot ID: | P78423 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 2000-1: 4000 | liver, lung cancer, tonsil |
Background
CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. The CX3CL1 is a leukocyte chemoattractant and expressed in various tissues .The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.
Images
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Immunohistochemistry of paraffin embedded human liver using cx3cl1 (GB111262) at dilution of 1:2000 (400x lens) |
| Immunohistochemistry of paraffin embedded human lung cancer using cx3cl1 (GB111262) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded human tonsil using cx3cl1 (GB111262) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
