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| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CXCR1 rabbit polyclonal antibody |
Gene Name: | C-X-C chemokine receptor type 1 |
Synonyms: | CXCR1, C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA, Interleukin 8 receptor, C-X-C motif chemokine receptor 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CXCR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 40 kDa |
Observed MW. | 45 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | pneumonia, splenitis |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | Immune spleen, spleen |
Background
CXCR1 is a chemokine receptor, which is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein-activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. Stimulation of CXCR1 in neutrophils by its primary ligand, Interleukin 8, leads to neutrophil chemotaxis and activation.
Images
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Western blot analysis of CXCR1 (GB11625) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse Immune spleen using CXCR1 (GB11625) at dilution of 1: 2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse spleen using CXCR1 (GB11625) at dilution of 1: 2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
