Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | C-X-C chemokine receptor type 2 |
Synonyms: | CD182, CDw128b, CMKAR2, CXC R2, CXCR 2, CXCR2, GRO/MGSA receptor, IL 8 receptor type 2, IL 8R B, IL8R2, IL8RA, IL8RB, IL-8RB, interleukin 8 receptor, beta |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CXCR2 |
Uniprot ID: | P35343 |
Isotype: | lgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 40 kDa / 41 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 500 | brain, testis, lung |
Background
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Images
WB analysis of CXCR2 (GB115557). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |