Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CYPIVF11 rabbit polyclonal |
Gene Name: | Cytochrome P450 4F11 |
Synonyms: | CYPIVF11, 3-hydroxy fatty acids omega-hydroxylase CYP4F11, Phylloquinone omega-hydroxylase CYP4F11, Docosahexaenoic acid omega-hydroxylase, CYP4F11 |
Immunogen: | Recombinant protein corresponding to Human CYPIVF11 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse | 1: 6000-1: 12000 | liver, kidney, striatum |
IF | Human, Mouse | 1: 500-1: 1000 | kidney, spleen, stomach |
Background
CYP4F11, also named as CYPIVF11, belongs to the cytochrome P450 family. It is the lone CYP4F/A enzyme that effectively oxidized 3-hydroxypalmitate. It is the predominant catalyst of this fatty acid oxidation reaction in human liver. CYP4F11 is one of the primary human epidermal keratinocytes. It is positively regulated by multiple signaling pathways in HaCaT keratinocytes, including RXR and JNK signaling pathways.
Images
Immunohistochemistry analysis of paraffin-embedded human liver using CYPIVF11 (GB112710) at dilution of 1: 12000 | |
Immunohistochemistry analysis of paraffin-embedded mouse kidney using CYPIVF11 (GB112710) at dilution of 1: 12000 | |
Immunohistochemistry analysis of paraffin-embedded mouse striatum using CYPIVF11 (GB112710) at dilution of 1: 12000 | |
Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using CYPIVF11 (GB112710) at dilution of 1: 1000 | |
Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using CYPIVF11 (GB112710) at dilution of 1: 1000 | |
Immunofluorescent analysis of paraformaldehyde-fixed mouse stomach using CYPIVF11 (GB112710) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |