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Anti-Calcitonin Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Calcitonin rabbit polyclonal antibody |
Gene Name: | Calcitonin |
Synonyms: | Calcitonin carboxyl-terminal peptide, CCP, PDN-21, CALCA, CALC1, katacalcin, KC, CGRP1 |
Immunogen: | Recombinant protein corresponding to Human Calcitonin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P01257 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 650-1: 1400 | breast, lung, thyroid gland |
Background
Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors.
Images
| Immunohistochemistry of paraffin embedded rat lung using Calcitonin (GB112577) at dilution of 1:700 (400x lens) |
| Immunohistochemistry of paraffin embedded rat thyroid gland using Calcitonin (GB112577) at dilution of 1:700 (400x lens) |
| Immunofluorescence of paraffin embedded mouse breast using Calcitonin (GB112577) at dilution of 1:650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
