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Anti-Caldesmon/CDM Mouse mAb (50 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | CALD1 CAD CDM |
| Protein Name: | Caldesmon (CDM) |
| Human Gene ID: | 800 |
| Uniprot ID: | Q05682 |
| Immunogen: | Synthesized peptide derived from human Caldesmon |
| Specificity: | This antibody detects endogenous levels of human Caldesmon |
| Source: | Mouse/IgG1, Kappa |
| Concentration: | 1 mg/ml |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
| Applications | Species | Dilution | |
| IHC、IF | Human | 1:200-1:500 |
Background
caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
Images
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Immunohistochemical analysis of paraffin-embedded Fibroid. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. |
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Immunohistochemical analysis of paraffin-embedded Liomyoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
