Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Calnexin |
Synonyms: | CANX |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Mouse Calnexin |
Uniprot ID: | P35564 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 67 kDa / 90 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 800 | brain, liver |
Background
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Images
Western blot analysis of Calnexin (GB115471) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |