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Anti-Calretinin Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Calretinin rabbit polyclonal antibody |
Gene Name: | Calretinin |
Synonyms: | CALB2, CAB29, CAL2, CR, calbindin 2, Calretinin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Calretinin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 29 kDa |
Observed MW. | 29 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, testis, cerebral cortex, |
Background
Calretinin also known as 29 kDa calbindin is a calcium-binding protein involved in calcium signaling. Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. Calretinin has an important role as a modulator of neuronal excitability including the induction of long-term potentiation. Loss of expression of calretinin in hippocampal interneurons has been suggested to be relevant in temporal lobe epilepsy. It is expressed in a number of other locations including hair follicles.
Images
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Western blot analysis of Calretinin (GB11680) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
