Your shopping cart is empty!
Anti-Calsequestrin 1 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Calsequestrin-1 |
Synonyms: | Calmitin, Calsequestrin 1, CASQ, CASQ1, PDIB1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Calsequestrin |
Uniprot ID: | O09165 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 55 kDa |
Product Usage Information
WB | Mouse | 1: 500-1: 1000 | lung, skeletal muscle |
Background
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions (By similarity). Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity).
Images
| Western blot analysis of Calsequestrin (GB115054) at dilution of 1: 1000 |
| Western blot analysis of Calsequestrin (GB115054) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
