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Anti-Caspase-12 Mouse mAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Caspase-12 |
Synonyms: | Casp12, CASP-12, CASP12P1, Inactive caspase-12, caspase 12 pseudogene 1, caspase 12 (gene/pseudogene) |
Immunogen: | Recombinant protein corresponding to Mouse Caspase-12 |
Uniprot ID: | O08736 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 48 kDa / 48 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | skin, stomach |
Background
Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels.
Images
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Western blot analysis of Caspase12 (GB12548) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
