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Anti-CoREST Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CoREST rabbit polyclonal |
Gene Name: | REST corepressor 1 |
Synonyms: | COREST, KIAA0071, Protein CoREST, RCOR, RCOR1, RCOR1Specific, Protein CoREST |
Immunogen: | Recombinant protein corresponding to Mouse CoREST |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 53 kDa |
Observed MW. | 53 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | testis, brain, lung |
Background
RCOR1, also named as REST corepressor 1, is a 485 amino acid protein, which belongs to the CoREST family. RCOR1 is a essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. The calculated molecular weight of RCOR1 is a 53 kDa, but the phosphorylated RCOR1 is about 60-65 kDa.
Images
 | Western blot analysis of CoREST (GB113633) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
