Reactivity: | M & H |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Gap junction beta-4 protein |
Synonyms: | Connexin 30.3, Cx30.3, GJB4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Connexin 30.3 / GJB4 |
Uniprot ID: | Q02738 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cell junction |
Predicted MW. / Observed MW. | 30 kDa / 30 kDa |
Product Usage Information
WB | Mouse | 1: 800-1: 1500 | lung, placenta |
IHC/IF | Human | 1: 800-1: 2400 | liver cancer, colon cancer |
Background
Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
Images
Western blot analysis of GJB4 (GB114880) at dilution of 1: 800 | |
Immunohistochemistry of paraffin embedded human Liver cancer using GJB4 (GB114880) at dilution of 1: 800 | |
Immunohistochemistry of paraffin embedded human colon cancer using GJB4 (GB114880) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |