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Anti-Connexin 43 / GJA1 Rabbit pAb (50 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Connexin 43 rabbit polyclonal |
Gene Name: | Gap junction alpha-1 protein |
Synonyms: | GJA1, AVSD3, CMDR, CX43, EKVP, GJAL, HLHS1, HSS, ODDD, PPKCA, gap junction protein alpha 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to human Connexin 43 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 43 kDa |
Observed MW. | 43 kDa |
Uniprot ID: | P17302, P08050, P23242 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | Rat cell |
Background
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract . May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.
Images
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All lanes are rat cell lysate Western blot analysis of Connexin 43 (GB13234-1) at dilution of 1:1000. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
