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| Reactivity: | H,M,R & H |
| Applications: | IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | C-terminal-binding protein 1 |
Synonyms: | brefeldin A-ribosylated substrate, BARS, CTBP, MGC104684, C-terminal-binding protein 1, CtBP1 |
Immunogen: | Recombinant protein corresponding to Mouse CtBP1 |
Uniprot ID: | O88712 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Images
IHC/IF | Human, Mouse, Rat | 1: 250-1: 1500 | colon, colon cancer, hippocampus |
ICC/IF | Human | 1:100-1:400 | HeLa |
Background
CTBP1 also named as C-terminal-binding protein 1 which belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. CTBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription.Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.
Images
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Immunohistochemistry of paraffin embedded human colon cancer using Ctbp1 (GB11987) at dilution of 1:1800 (200x lens) |
 | Immunohistochemistry of paraffin embedded mouse small intestine using Ctbp1 (GB11987) at dilution of 1:1800 (300x lens) |
 | Immunohistochemistry of paraffin embedded mouse uterus using Ctbp1 (GB11987) at dilution of 1:600 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat uterus using Ctbp1 (GB11987) at dilution of 1:600 (300x lens) |
 | Immunohistochemistry of paraffin embedded rat uterus using Ctbp1 (GB11987) at dilution of 1:1800 (350x lens) |
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Immunofluorescence of paraffin embedded mouse hippocampus using Ctbp1 (GB11987) at dilution of 1:500 (200x lens) |
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Immunofluorescence of paraffin embedded rat colon using Ctbp1 (GB11987) at dilution of 1:500 (200x lens) |
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Immunofluorescence of paraffin embedded rat uterus using Ctbp1 (GB11987) at dilution of 1:500 (200x lens) |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using CtBP1(GB11987) at dilution of 1:100-1:400 |
| ICC analysis of CtBP1(GB11987)red. Sample: HeLa, 4% PFA (G1101) 20min. Primary antibody: 1: 400, 4°C overnight. Secondary antibody: Cy3 conjugated Goat Anti-Rabbit IgG (H+L) (GB21303), 1: 300, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
