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Anti-Cyclin A2 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M |
| Applications: | IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cyclin-A2 |
Synonyms: | Cyclin-A, Ccna2, CycA, CycA2, Cyclin A2, Cyclin A, CCNA2, CCNA, CCN1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cyclin A2 |
Uniprot ID: | P51943 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Images
IHC/IF | Mouse, Rat | 1: 800-1: 1600 | lung, ovary, placenta |
ICC/IF | Human, Mouse | 1: 50-1: 200 | HeLa |
Background
Cyclin A2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. Cyclin A2 binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Cyclin A2 could be phosphorylated during the G2/M.
Images
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Immunohistochemistry of paraffin embedded mouse placenta using Cyclin-A2 (GB111228) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using Cyclin-A2 (GB111228) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse uterus using Cyclin-A2 (GB111228) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using Cyclin-A2 (GB111228) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse ovary using Cyclin-A2 (GB111228) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse placenta using Cyclin-A2 (GB111228) at dilution of 1:800 (400x lens) |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using Cyclin A2(GB111228) at dilution of 1:50-1:200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
