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Anti-Cyclophilin A Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Peptidyl-prolyl cis-trans isomerase A |
Synonyms: | PPIase A, Cyclophilin A, Ppia, Cyclosporin A-binding protein, Rotamase A, SP18 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cyclophilin A |
Uniprot ID: | P17742 |
Isotype: | IgG1,k |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 18 kDa / 18 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | Jurkat, thymus, brain |
Background
Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.
Images
| WB analysis of Cyclophilin A(GB121283). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
