Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Cystatin C rabbit polyclonal antibody |
Gene Name: | Cystatin-C |
Synonyms: | Cystatin-3, Cst3, AD8, ARMD11, CYTC, Epididymis secretory protein Li 2, Gamma trace, HCCAA, MGC117328, Neuroendocrine basic polypeptide, Post gamma globulin |
Immunogen: | Recombinant protein corresponding to Mouse Cystatin C |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 16 kDa |
Observed MW. | 14 kDa |
Uniprot ID: | P21460 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | testis, spleen, brain |
Background
Cystatin C is a inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. It is also used as an emerging biomarker in cardiovascular disease. Cystatin C is involved in a variety of inflammatory reactions. The concentration of serum cystatin C has also been shown to be unaltered in certain inflammatory conditions or other disorders of metabolism. The plasma level of serum cystatin C can be expressed as its level of generation from cells and diet and its subsequent elimination through the gut, liver, and kidneys.
Images
Western blot analysis of Cystatin-C (GB111376) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |