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Anti-Cytochrome P450 2E1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cytochrome P450 2E1 |
Synonyms: | 4 nitrophenol 2 hydroxylase, CPE1, CYP2E, CYP2E1, CYP-2E1, CYP2E1-Specific, CYPIIE1, Cytochrome P450 2E1, Cytochrome P450 J, P450 J, P450C2E |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome P450 2E1 |
Uniprot ID: | Q05421 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum membrane |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 100-1: 200 | colon, liver |
Background
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
Images
| IHC analysis of CytochromeP4502E1 (GB115524). |
| IHC analysis of CytochromeP4502E1 (GB115524). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
