Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Keratin, type II cytoskeletal 1 |
Synonyms: | Cytokeratin-1, CK-1, Keratin-1, K1, Type-II keratin Kb1, Krt1, Kb1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CK1 |
Uniprot ID: | P04264 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1500 | cervical cancer, tonsil |
Background
The protein encoded by this gene is a member of the keratin gene family, a type II cytokeratins composed of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.
Images
Immunohistochemistry analysis of paraffin embedded human cervical cancer using CK1 (GB121018) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human non-small cell lung cancer using CK1 (GB121018) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human tonsil using CK1 (GB121018) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |