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Anti-Cytokeratin 1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cytokeratin 1 rabbit polyclonal antibody |
Gene Name: | Keratin, type II cytoskeletal 1 |
Synonyms: | Cytokeratin-1, CK-1, Keratin-1, K1, Type-II keratin Kb1, Krt1, Kb1 |
Immunogen: | Recombinant protein corresponding to Mouse Cytokeratin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P04104, Q6IMF3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 4000 | breast cancer, oral mucosa, skin |
Background
The protein encoded by this gene is a member of the keratin gene family, a type II cytokeratins composed of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using Cytokeratin-1 (GB111277) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse skin using Cytokeratin-1 (GB111277) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat oral mucosa using Cytokeratin-1 (GB111277) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat skin using Cytokeratin-1 (GB111277) at dilution of 1:2000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse skin using Cytokeratin-1 (GB111277) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded rat skin using Cytokeratin-1 (GB111277) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
