Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Cytokeratin 10 rabbit polyclonal antibody |
Gene Name: | Keratin, type I cytoskeletal 10 |
Synonyms: | 56 kDa cytokeratin, Cytokeratin-10, CK-10, Keratin-10, Krt10, K10, BCIE, BIE |
Immunogen: | Recombinant protein corresponding to Mouse Cytokeratin 10 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell surface |
Uniprot ID: | Q6IFW6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 1000-1: 4000 | skin, stomach |
Background
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. As a type I keratin, keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia.
Images
Immunohistochemistry of paraffin embedded rat stomach using CK10 (GB111413) at dilution of 1:2000 (200x lens) |
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Immunohistochemistry of paraffin embedded rat skin using CK10 (GB111413) at dilution of 1:2000 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |