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Anti-Cytokeratin 19 Mouse mAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Keratin, type I cytoskeletal 19 |
Synonyms: | Cytokeratin-19, CK-19, Keratin-19, K19, Krt19, Krt1-19, 40 kDa keratin intermediate filament, K1CS |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CK19 |
Uniprot ID: | P08727 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. / Observed MW. | 44kDa / 44kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HT29, MCF7, T-47D, SW480 |
IHC/IF | Human | 1: 500-1: 1000 | breast cancer, lung adenocarcinoma, gastric carcinoma |
Background
Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Depending on the assays, KRT19 has been shown to be both a specific and a non-specific marker.
Images
| Western blot analysis of Cytokeratin 19 (GB12198) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human gastric carcinoma using Cytokeratin 19 (GB12198) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using Cytokeratin 19 (GB12198) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded human breast cancer using Cytokeratin 19 (GB12198) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded human lung adenocarcinoma using Cytokeratin 19 (GB12198) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded human gastric carcinoma using Cytokeratin 19 (GB12198) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
