Reactivity: | H |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Keratin, type I cytoskeletal 19 |
Synonyms: | Cytokeratin-19, CK-19, Keratin-19, K19, Krt19, Krt1-19, 40 kDa keratin intermediate filament, K1CS |
Immunogen: | KLH conjugated Synthetic peptidecorresponding to Human Cytokeratin 19 |
Uniprot ID: | P08727 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 45 kDa / 45 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HT-29, T-47d, MCF-7 |
Background
Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Depending on the assays, KRT19 has been shown to be both a specific and a non-specific marker.
Images
Western blot analysis of CK19(GB122161) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |