Reactivity: | M,R & M,R |
Applications: | IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Cytokeratin 6 rabbit polyclonal |
Gene Name: | Keratin, type II cytoskeletal 6A |
Synonyms: | Krt6a, KRT6A, CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D, PC3, CK-6C, CK-6E, keratin 6A |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1:500-1:3000 | skin, stomach |
IF | Mouse, Rat | 1:250-1:500 | skin, stomach |
Background
Keratin 6A is a member of the keratin gene family which is one of the 27 different type II keratinsis. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia.
Images
Immunohistochemistry analysis of paraffin-embedded rat skin using Cytokeratin 6 (GB11800) at dilution of 1: 500 |
|
Immunohistochemistry analysis of paraffin-embedded mouse skin using Cytokeratin 6 (GB11800) at dilution of 1: 500 |
|
Immunohistochemistry analysis of paraffin-embedded mouse stomach using Cytokeratin 6 (GB11800) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |