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Anti-DENND1A Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | DENN domain-containing protein 1A |
Synonyms: | Connecdenn, DENN/MADD domain containing 1A, DENND1A, FAM31A, KIAA1608, Protein FAM31A, RP11 230L22.3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DENND1A |
Uniprot ID: | Q8K382 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 112 kDa / 112 kDa |
Product Usage Information
WB | Human, Mouse | 1: 1000-1: 2000 | skeletal muscle |
Background
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes . Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P.
Images
| Western blot analysis of DENND1A (GB115146) at dilution of 1: 1000 |
| Western blot analysis of DENND1A (GB115146) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
