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Anti-DHX58/RLR Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DHX58 rabbit polyclonal antibody |
Gene Name: | Probable ATP-dependent RNA helicase DHX58 |
Synonyms: | Probable ATP-dependent helicase LGP2, Protein D11Lgp2 homolog, RIG-I-like receptor 3, RLR-3, RIG-I-like receptor LGP2, RLR, DHX58, D11LGP2E, LGP2 |
Immunogen: | Recombinant protein corresponding to Mouse DHX58 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 77 kDa |
Observed MW. | 77 kDa |
Uniprot ID: | Q96C10 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, HepG2, T-47D, SK-BR-3 |
Background
DHX58(Probable ATP-dependent RNA helicase DHX58) is also named as D11LGP2E, LGP2 and belongs to the RLR subfamily. DHX58, originally identified as a highly expressed gene in mammary tumors, is another cytoplasmic DEX(D/H)-box helicase that can recognize RNA(PMID: 18411269). It acts as a positive, but not negative, regulator of RIG-I– and MDA5-dependent recognition of RNA virus infection and plays a pivotal role in antiviral responses in vivo.
Images
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Western blot analysis of LGP2 (GB111479) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
