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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Delta-like protein 4 |
Synonyms: | Delta like protein 4, delta like 4 (Drosophila), Delta4, DLL4, Drosophila Delta homolog 4, hdelta2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DLL4 |
Uniprot ID: | Q9JI71 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 74 kDa / 75-80 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 400 | brain |
Background
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
Images
| Western blot analysis of DLL4 (GB115572) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
