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| Reactivity: | H |
| Applications: | IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DSPP rabbit polyclonal |
Gene Name: | Dentin sialophosphoprotein |
Synonyms: | Dentin matrix protein 3, DMP-3, Dentin phosphophoryn, DPP, DSP, Dspp, Dmp3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DSPP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IF | Human | 1: 500-1: 1000 | lung cancer, breast cancer |
Background
This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene.
Images
| Immunofluorescent analysis of paraformaldehyde-fixed human lung cancer using DSPP (GB112965) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human breast cancer using DSPP (GB112965) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
