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Anti-DYRK3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Dual specificity tyrosine-phosphorylation-regulated kinase 3 |
Synonyms: | hYAK3-2, RED, REDK |
Immunogen: | Recombinant protein corresponding to Mouse DYRK3 |
Uniprot ID: | Q922Y0 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 66 kDa / 63-65 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 500 | liver |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 3000 | testis, colon |
Background
Dual-specificity protein kinase that promotes disassembly of several types of membraneless organelles during mitosis, such as stress granules, nuclear speckles and pericentriolar material (By similarity). Dual-specificity tyrosine-regulated kinases (DYRKs) autophosphorylate a critical tyrosine residue in their activation loop and phosphorylate their substrate on serine and threonine residues.
Images
| Western blot analysis of DYRK3 (GB114521) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse testis using DYRK3 (GB114521) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded rat testis using DYRK3 (GB114521) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded rat colon using DYRK3 (GB114521) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
