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| Reactivity: | H,M,R,dog |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EGFR rabbit polyclonal |
Gene Name: | Epidermal growth factor receptor |
Synonyms: | EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to human EGFR |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 134 kDa |
Observed MW. | 175 kDa |
Uniprot ID: | P00533, Q01279 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human,Mouse,Rat, dog | 1:500-1:1000 | Dog tissue lysate |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Images
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All lanes are dog tissue lysate Western blot analysis of EGFR (GB13084-1) at dilution of 1:1000. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |