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Anti-EIF2G/EIF2S3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EIF2G/EIF2S3 rabbit polyclonal |
Gene Name: | Eukaryotic translation initiation factor 2 subunit 3 |
Synonyms: | Eif-2-gamma X, eIF 2gA, eIF-2gX, EIF2, EIF2G, EIF2gamma, EIF2S3, Eukaryotic translation initiation factor 2 subunit gamma X |
Immunogen: | Recombinant protein corresponding to Mouse EIF2G/EIF2S3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 51 kDa |
Observed MW. | 51 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | NIH/3T3, PC-12 |
Background
Interacts with GTP and initiator methionyl-tRNA, translation initiation factor eIF2 forms a ternary complex that binds the 40S ribosome and then scans an mRNA to select the AUG start codon for protein synthesis. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. EIF2S3 is the core subunit of the heterotrimeric eIF2 complex.
Images
 | Western blot analysis of EIF2S3 (GB113640) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
