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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | ER membrane protein complex subunit 8 |
Synonyms: | C16orf2, C16orf4, COX4 neighbor, COX4AL, COX4NB, EMC8, FAM158B, Neighbor of COX4, NOC4 |
Immunogen: | Recombinant protein corresponding to Mouse EMC8 |
Uniprot ID: | O70378 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 23 kDa / 24 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 800 | thymus, testis, kidney |
Background
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.
Images
| Western blot analysis of EMC8 (GB114542) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
