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| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ERAS rabbit polyclonal |
Gene Name: | GTPase ERas |
Synonyms: | E-Ras, Embryonic stem cell-expressed Ras, Eras, ecat5, HRAS2, HRASP, Small GTPase protein E Ras, v Ha ras Harvey rat sarcoma viral oncogene homolog 2, ES cell expressed Ras |
Immunogen: | Recombinant protein corresponding to Mouse ERAS |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Rat | 1: 500-1: 1000 | testis |
Background
ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.
Images
 | Western blot analysis of ERAS (GB113047) at dilution of 1: 100 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
