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Anti-ERp57 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Protein disulfide-isomerase A3 |
Synonyms: | 58 kDa microsomal protein, Disulfide isomerase ER 60, ER protein 57, ER protein 60, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PDIA3, PI PLC, Protein disulfide isomerase A3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ERp57 |
Uniprot ID: | P27773 |
Isotype: | lgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 57 kDa / 57 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 600 | liver, brain, testis |
Background
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Images
| WB analysis of PDIA3 (GB115554). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
