Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Eyes absent homolog 1 |
Synonyms: | BOP, BOR, EYA1, Eyes absent homolog 1 |
Immunogen: | Recombinant protein corresponding to Mouse EYA1 |
Uniprot ID: | P97767 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 64 kDa / 60-65 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 500 | brain |
Background
Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 . Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress .
Images
| Western blot analysis of EYA1 (GB114522) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
